Showing posts with label heparin. Show all posts
Showing posts with label heparin. Show all posts

Thursday, August 8, 2019

Heparin Shortage: 2019



Link to Abstract

Imminent risk of a global shortage of heparin caused by the African Swine Fever afflicting the Chinese pig herd

By no means am I a fear mongering here, but I am legitimately concerned about the inaction of our health care systems to worry about this issue until it was too late. We were warned last year. It's now August. Heparin is on backorder, folks. I know you and I are going to be just fine but our patients may suffer. This is a good time to check out which of your patients could be switched from heparin to lovenox/enoxaparin, fondaparinux/arixtra, and other alternatives. Remember that there are certain vascular surgery and cardiothoracic procedures where there are no alternatives for heparin and we need to make sure that these patients have the medication they need as we try to weather the storm. Have you all had meetings yet to address this issue at your shop? Nurses, have you been kept in the loop of these impending issues? Pharmacists, am I overreacting?

-EJ

Other links:
https://www.ashp.org/drug-shortages/current-shortages/Drug-Shortage-Detail.aspx?id=353
https://www.upi.com/Top_News/US/2019/05/01/Chinas-African-swine-fever-epidemic-could-cause-global-heparin-shortage/5881556646708/
https://www.raps.org/news-and-articles/news-articles/2018/2/concern-over-heparin-supply-prompts-call-for-fda-i
https://www.reuters.com/article/us-congress-heparin-china/congress-seeks-briefing-on-potential-threat-to-u-s-heparin-supply-idUSKCN1UP1TX
https://www.fiercepharma.com/manufacturing/congress-hits-panic-button-over-potential-shortage-chinese-heparin-as-chinese-swine


Estimated Resupply Dates per "https://www.ashp.org/drug-shortages/current-shortages/Drug-Shortage-Detail.aspx?id=353"

•Fresenius Kabi has heparin 5,000 unit/mL 10 mL vials on back order and the company estimates a release date of mid- to late-August 2019. The 5,000 unit/mL 1 mL syringes are on back order and the company estimates a release date of mid-August 2019. The 10,000 unit/mL 4 mL vials are on back order and the company cannot estimate a release date. There are short-dated 20,000 unit/mL 1 mL vials available with an expiration date of < 7 months. All other presentations are on allocation.
•Hikma has 1,000 unit/mL 2 mL vials, 5,000 unit/mL 2 mL vials, and 10,000 unit/mL 2 mL vials on allocation.
•Pfizer has 5,000 unit/mL 1 mL Carpuject syringes on back order and the company estimates a release date of August 2019. The 5,000 unit/mL 1 mL glass vials are on back order and the company estimates a release date of August 2019. The 5,000 unit/mL 10 mL vials are on back order and the company estimates a release date of December 2019. The 1,000 unit/mL 10 mL glass vials are on back order and the company estimates a release date of December 2019. The 1,000 unit/mL 30 mL vials are on back order and the company estimates a release date of August 2019. The 10,000 unit/mL 0.5 mL Carpuject syringes are available in limited supply. The 1,000 unit/mL 10 mL vials (NDC 00069-0058-01) are available in limited supply.

•Sagent has 1,000 unit/mL 2 mL and 10 mL vials on back order and the company estimates a release date of August 2019. The 1,000 unit/mL 1 mL and 30 mL vials are on back order and the company estimates a release date of September 2019. The 5,000 unit/mL 1 mL and 10 mL vials are on back order and the company estimates a release date of August 2019. The 10,000 unit/mL 1 mL and 4 mL vials are on back order and the company estimates a release date of August 2019.

Sunday, July 14, 2019

Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis



Link to Abstract. Not a free article. :(

This is a question I would always ask myself as I would check off the boxes on admission orders as a resident, not as a fellow because the residents do it, and sometimes now as an attending. I always thought it was a waste of resources and uncomfortable to the patients to not only inject them with pharmacological DVTs prophylaxis, but also burden them with those SCDs. I’m really grateful for my colleagues in Saudi Arabia for putting together this study and sealing the deal for me as to how to manage this moving forward. A definite 🎩 tip to them

-EJ